Zope
Very nice article about Zope Hosting and Performance from author who provides professional Zope hosting for some years running systems that range in the 2000-3000 hits per minute scale. He put together some of the stuff He learnt (sometimes the hard way) about Zope performance.
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Here is description of Zope found in mailing lists. Author: Terry Hancock.
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Running one instance but using a separate db file for each instance. A single zope instance consums less memory. Add and mount a data.fs for every plone instance. It's very easy using zope 2.7:
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Lennart Regebro welcomes the fact that Zope 3 rewrites many things in Zope that were showing their age. But what won't automatically be solved with Zope 3, he believes, is people's tendency in the Zope community to first of all do things their own way, and secondly, not move these "own ways" into the common codebase, even when they could be of use to others
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